Hugues Ouellet to Binding Sites
                            
                            
                                This is a "connection" page, showing publications Hugues Ouellet has written about Binding Sites.
                            
                            
                            
                                
                                    
                                            
    
        
        
        
            Connection Strength
            
                
            
            0.387
         
        
        
     
 
    
        
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            Ouellet H, Kells PM, Ortiz de Montellano PR, Podust LM. Reverse type I inhibitor of Mycobacterium tuberculosis CYP125A1. Bioorg Med Chem Lett. 2011 Jan 01; 21(1):332-7.
            
            
                Score: 0.082
             
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            Ouellet H, Guan S, Johnston JB, Chow ED, Kells PM, Burlingame AL, Cox JS, Podust LM, de Montellano PR. Mycobacterium tuberculosis CYP125A1, a steroid C27 monooxygenase that detoxifies intracellularly generated cholest-4-en-3-one. Mol Microbiol. 2010 Aug; 77(3):730-42.
            
            
                Score: 0.080
             
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            Ouellet H, Podust LM, de Montellano PR. Mycobacterium tuberculosis CYP130: crystal structure, biophysical characterization, and interactions with antifungal azole drugs. J Biol Chem. 2008 Feb 22; 283(8):5069-80.
            
            
                Score: 0.067
             
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            Ouellet H, Milani M, LaBarre M, Bolognesi M, Couture M, Guertin M. The roles of Tyr(CD1) and Trp(G8) in Mycobacterium tuberculosis truncated hemoglobin O in ligand binding and on the heme distal site architecture. Biochemistry. 2007 Oct 16; 46(41):11440-50.
            
            
                Score: 0.066
             
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            Ouellet H, Juszczak L, Dantsker D, Samuni U, Ouellet YH, Savard PY, Wittenberg JB, Wittenberg BA, Friedman JM, Guertin M. Reactions of Mycobacterium tuberculosis truncated hemoglobin O with ligands reveal a novel ligand-inclusive hydrogen bond network. Biochemistry. 2003 May 20; 42(19):5764-74.
            
            
                Score: 0.049
             
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            Podust LM, von Kries JP, Eddine AN, Kim Y, Yermalitskaya LV, Kuehne R, Ouellet H, Warrier T, Altek?ster M, Lee JS, Rademann J, Oschkinat H, Kaufmann SH, Waterman MR. Small-molecule scaffolds for CYP51 inhibitors identified by high-throughput screening and defined by X-ray crystallography. Antimicrob Agents Chemother. 2007 Nov; 51(11):3915-23.
            
            
                Score: 0.016
             
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            Dantsker D, Samuni U, Ouellet Y, Wittenberg BA, Wittenberg JB, Milani M, Bolognesi M, Guertin M, Friedman JM. Viscosity-dependent relaxation significantly modulates the kinetics of CO recombination in the truncated hemoglobin TrHbN from Mycobacterium tuberculosis. J Biol Chem. 2004 Sep 10; 279(37):38844-53.
            
            
                Score: 0.013
             
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            Milani M, Ouellet Y, Ouellet H, Guertin M, Boffi A, Antonini G, Bocedi A, Mattu M, Bolognesi M, Ascenzi P. Cyanide binding to truncated hemoglobins: a crystallographic and kinetic study. Biochemistry. 2004 May 11; 43(18):5213-21.
            
            
                Score: 0.013