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Connection

Renato J. Aguilera to Apoptosis

This is a "connection" page, showing publications Renato J. Aguilera has written about Apoptosis.
Connection Strength

3.990
  1. Borrego EA, Guerena CD, Schiaffino Bustamante AY, Gutierrez DA, Valenzuela CA, Betancourt AP, Varela-Ramirez A, Aguilera RJ. A Novel Pyrazole Exhibits Potent Anticancer Cytotoxicity via Apoptosis, Cell Cycle Arrest, and the Inhibition of Tubulin Polymerization in Triple-Negative Breast Cancer Cells. Cells. 2024 Jul 20; 13(14).
    View in: PubMed
    Score: 0.565
  2. Contreras L, Medina S, Schiaffino Bustamante AY, Borrego EA, Valenzuela CA, Das U, Karki SS, Dimmock JR, Aguilera RJ. Three novel piperidones exhibit tumor-selective cytotoxicity on leukemia cells via protein degradation and stress-mediated mechanisms. Pharmacol Rep. 2022 Feb; 74(1):159-174.
    View in: PubMed
    Score: 0.463
  3. Villanueva PJ, Martinez A, Baca ST, DeJesus RE, Larragoity M, Contreras L, Gutierrez DA, Varela-Ramirez A, Aguilera RJ. Pyronaridine exerts potent cytotoxicity on human breast and hematological cancer cells through induction of apoptosis. PLoS One. 2018; 13(11):e0206467.
    View in: PubMed
    Score: 0.381
  4. Contreras L, Calderon RI, Varela-Ramirez A, Zhang HY, Quan Y, Das U, Dimmock JR, Skouta R, Aguilera RJ. Induction of apoptosis via proteasome inhibition in leukemia/lymphoma cells by two potent piperidones. Cell Oncol (Dordr). 2018 Dec; 41(6):623-636.
    View in: PubMed
    Score: 0.374
  5. Robles-Escajeda E, Das U, Ortega NM, Parra K, Francia G, Dimmock JR, Varela-Ramirez A, Aguilera RJ. A novel curcumin-like dienone induces apoptosis in triple-negative breast cancer cells. Cell Oncol (Dordr). 2016 Jun; 39(3):265-77.
    View in: PubMed
    Score: 0.316
  6. Varela-Ramirez A, Costanzo M, Carrasco YP, Pannell KH, Aguilera RJ. Cytotoxic effects of two organotin compounds and their mode of inflicting cell death on four mammalian cancer cells. Cell Biol Toxicol. 2011 Jun; 27(3):159-68.
    View in: PubMed
    Score: 0.218
  7. Mart?nez A, Rajapakse CS, S?nchez-Delgado RA, Varela-Ramirez A, Lema C, Aguilera RJ. Arene-Ru(II)-chloroquine complexes interact with DNA, induce apoptosis on human lymphoid cell lines and display low toxicity to normal mammalian cells. J Inorg Biochem. 2010 Sep; 104(9):967-77.
    View in: PubMed
    Score: 0.212
  8. ElMorsy SM, Gutierrez DA, Valdez S, Kumar J, Aguilera RJ, Noufal M, Sarma H, Chinnam S, Narayan M. Graphene acid quantum dots: A highly active multifunctional carbon nano material that intervene in the trajectory towards neurodegeneration. J Colloid Interface Sci. 2024 Sep 15; 670:357-363.
    View in: PubMed
    Score: 0.140
  9. Swain RM, Sanchez A, Gutierrez DA, Varela-Ramirez A, Aguilera RJ. Thiophene derivative inflicts cytotoxicity via an intrinsic apoptotic pathway on human acute lymphoblastic leukemia cells. PLoS One. 2023; 18(12):e0295441.
    View in: PubMed
    Score: 0.136
  10. Swain RM, Contreras L, Varela-Ramirez A, Hossain M, Das U, Valenzuela CA, Penichet ML, Dimmock JR, Aguilera RJ. Two novel piperidones induce apoptosis and antiproliferative effects on human prostate and lymphoma cancer cell lines. Invest New Drugs. 2022 Oct; 40(5):905-921.
    View in: PubMed
    Score: 0.123
  11. Nakamura-Bencomo S, Gutierrez DA, Robles-Escajeda E, Iglesias-Figueroa B, Siqueiros-Cend?n TS, Espinoza-S?nchez EA, Ar?valo-Gallegos S, Aguilera RJ, Rasc?n-Cruz Q, Varela-Ramirez A. Recombinant human lactoferrin carrying humanized glycosylation exhibits antileukemia selective cytotoxicity, microfilament disruption, cell cycle arrest, and apoptosis activities. Invest New Drugs. 2021 04; 39(2):400-415.
    View in: PubMed
    Score: 0.109
  12. Lyon CJ, Evans CJ, Bill BR, Otsuka AJ, Aguilera RJ. The C. elegans apoptotic nuclease NUC-1 is related in sequence and activity to mammalian DNase II. Gene. 2000 Jul 11; 252(1-2):147-54.
    View in: PubMed
    Score: 0.107
  13. Iglesias-Figueroa BF, Siqueiros-Cend?n TS, Gutierrez DA, Aguilera RJ, Espinoza-S?nchez EA, Ar?valo-Gallegos S, Varela-Ramirez A, Rasc?n-Cruz Q. Recombinant human lactoferrin induces apoptosis, disruption of F-actin structure and cell cycle arrest with selective cytotoxicity on human triple negative breast cancer cells. Apoptosis. 2019 08; 24(7-8):562-577.
    View in: PubMed
    Score: 0.100
  14. Montoya A, Varela-Ramirez A, Dickerson E, Pasquier E, Torabi A, Aguilera R, Nahleh Z, Bryan B. The beta adrenergic receptor antagonist propranolol alters mitogenic and apoptotic signaling in late stage breast cancer. Biomed J. 2019 06; 42(3):155-165.
    View in: PubMed
    Score: 0.100
  15. Gutierrez DA, DeJesus RE, Contreras L, Rodriguez-Palomares IA, Villanueva PJ, Balderrama KS, Monterroza L, Larragoity M, Varela-Ramirez A, Aguilera RJ. A new pyridazinone exhibits potent cytotoxicity on human cancer cells via apoptosis and poly-ubiquitinated protein accumulation. Cell Biol Toxicol. 2019 12; 35(6):503-519.
    View in: PubMed
    Score: 0.097
  16. Robles-Escajeda E, Mart?nez A, Varela-Ramirez A, S?nchez-Delgado RA, Aguilera RJ. Analysis of the cytotoxic effects of ruthenium-ketoconazole and ruthenium-clotrimazole complexes on cancer cells. Cell Biol Toxicol. 2013 Dec; 29(6):431-43.
    View in: PubMed
    Score: 0.068
  17. Shaik N, Mart?nez A, Augustin I, Giovinazzo H, Varela-Ram?rez A, Sana? M, Aguilera RJ, Contel M. Synthesis of apoptosis-inducing iminophosphorane organogold(III) complexes and study of their interactions with biomolecular targets. Inorg Chem. 2009 Feb 16; 48(4):1577-87.
    View in: PubMed
    Score: 0.049
  18. Montoya J, Varela-Ramirez A, Estrada A, Martinez LE, Garza K, Aguilera RJ. A fluorescence-based rapid screening assay for cytotoxic compounds. Biochem Biophys Res Commun. 2004 Dec 24; 325(4):1517-23.
    View in: PubMed
    Score: 0.036
  19. Evans CJ, Aguilera RJ. DNase II: genes, enzymes and function. Gene. 2003 Dec 11; 322:1-15.
    View in: PubMed
    Score: 0.034
  20. Jain PM, Gutierrez DA, Kumar S, Aguilera RJ, Karki SS. Synthesis of Novel Pyrazole-Oxindole Conjugates with Cytotoxicity in Human Cancer Cells via Apoptosis. Chem Biodivers. 2023 Sep; 20(9):e202300843.
    View in: PubMed
    Score: 0.033
  21. Chhikara A, Roayapalley PK, Sakagami H, Amano S, Satoh K, Uesawa Y, Das U, Das S, Borrego EA, Guerena CD, Hernandez CR, Aguilera RJ, Dimmock JR. Novel Unsymmetric 3,5-Bis(benzylidene)-4-piperidones That Display Tumor-Selective Toxicity. Molecules. 2022 Oct 09; 27(19).
    View in: PubMed
    Score: 0.031
  22. Roayapalley PK, Dimmock JR, Contreras L, Balderrama KS, Aguilera RJ, Sakagami H, Amano S, Sharma RK, Das U. Design, Synthesis and Tumour-Selective Toxicity of Novel 1-[3-{3,5-Bis(benzylidene)-4-oxo-1-piperidino}-3-oxopropyl]-4-piperidone Oximes and Related Quaternary Ammonium Salts. Molecules. 2021 Nov 25; 26(23).
    View in: PubMed
    Score: 0.029
  23. Tilekar K, Hess JD, Upadhyay N, Bianco AL, Schweipert M, Laghezza A, Loiodice F, Meyer-Almes FJ, Aguilera RJ, Lavecchia A, C S R. Thiazolidinedione "Magic Bullets" Simultaneously Targeting PPAR? and HDACs: Design, Synthesis, and Investigations of their In Vitro and In Vivo Antitumor Effects. J Med Chem. 2021 05 27; 64(10):6949-6971.
    View in: PubMed
    Score: 0.028
  24. Choodamani B, Cano Hernandez KG, Kumar S, Tony AM, Schiaffino Bustamante AY, Aguilera RJ, Schols D, Gopi Mohan C, Karki SS. Synthesis, Molecular Docking and Preliminary Antileukemic Activity of 4-Methoxybenzyl Derivatives Bearing Imidazo[2,1-b][1,3,4]thiadiazole. Chem Biodivers. 2021 Feb; 18(2):e2000800.
    View in: PubMed
    Score: 0.028
  25. Tilekar K, Upadhyay N, Schweipert M, Hess JD, Macias LH, Mrowka P, Meyer-Almes FJ, Aguilera RJ, Iancu CV, Choe JY, Ramaa CS. Permuted 2,4-thiazolidinedione (TZD) analogs as GLUT inhibitors and their in-vitro evaluation in leukemic cells. Eur J Pharm Sci. 2020 Nov 01; 154:105512.
    View in: PubMed
    Score: 0.027
  26. Tilekar K, Upadhyay N, Hess JD, Macias LH, Mrowka P, Aguilera RJ, Meyer-Almes FJ, Iancu CV, Choe JY, Ramaa CS. Structure guided design and synthesis of furyl thiazolidinedione derivatives as inhibitors of GLUT 1 and GLUT 4, and evaluation of their anti-leukemic potential. Eur J Med Chem. 2020 Sep 15; 202:112603.
    View in: PubMed
    Score: 0.027
  27. Donoso-Bustamante V, Borrego EA, Schiaffino-Bustamante Y, Guti?rrez DA, Millas-Vargas JP, Fuentes-Retamal S, Correa P, Carrillo I, Aguilera RJ, Miranda D, Ch?vez-B?ez I, Pulgar R, Urra FA, Varela-Ram?rez A, Araya-Maturana R. An acylhydroquinone derivative produces OXPHOS uncoupling and sensitization to BH3 mimetic ABT-199 (Venetoclax) in human promyelocytic leukemia cells. Bioorg Chem. 2020 07; 100:103935.
    View in: PubMed
    Score: 0.026
  28. Upadhyay N, Tilekar K, J?nsch N, Schweipert M, Hess JD, Henze Macias L, Mrowka P, Aguilera RJ, Choe JY, Meyer-Almes FJ, Ramaa CS. Discovery of novel N-substituted thiazolidinediones (TZDs) as HDAC8 inhibitors: in-silico studies, synthesis, and biological evaluation. Bioorg Chem. 2020 07; 100:103934.
    View in: PubMed
    Score: 0.026
  29. Solis LH, Ayala Y, Portillo S, Varela-Ramirez A, Aguilera R, Boland T. Thermal inkjet bioprinting triggers the activation of the VEGF pathway in human microvascular endothelial cells in vitro. Biofabrication. 2019 07 09; 11(4):045005.
    View in: PubMed
    Score: 0.025
  30. Santiago-Vazquez Y, Das S, Das U, Robles-Escajeda E, Ortega NM, Lema C, Varela-Ram?rez A, Aguilera RJ, Balzarini J, De Clercq E, Dimmock SG, Gorecki DK, Dimmock JR. Novel 3,5-bis(arylidene)-4-oxo-1-piperidinyl dimers: structure-activity relationships and potent antileukemic and antilymphoma cytotoxicity. Eur J Med Chem. 2014 Apr 22; 77:315-22.
    View in: PubMed
    Score: 0.017
  31. Pedroza DA, De Leon F, Varela-Ramirez A, Lema C, Aguilera RJ, Mito S. The cytotoxic effect of 2-acylated-1,4-naphthohydroquinones on leukemia/lymphoma cells. Bioorg Med Chem. 2014 Jan 15; 22(2):842-7.
    View in: PubMed
    Score: 0.017
  32. Robles-Escajeda E, Lerma D, Nyakeriga AM, Ross JA, Kirken RA, Aguilera RJ, Varela-Ramirez A. Searching in mother nature for anti-cancer activity: anti-proliferative and pro-apoptotic effect elicited by green barley on leukemia/lymphoma cells. PLoS One. 2013; 8(9):e73508.
    View in: PubMed
    Score: 0.017
  33. Oldham ED, Seelam S, Lema C, Aguilera RJ, Fiegel J, Rankin SE, Knutson BL, Lehmler HJ. Synthesis, surface properties, and biocompatibility of 1,2,3-triazole-containing alkyl ?-D-xylopyranoside surfactants. Carbohydr Res. 2013 Sep 20; 379:68-77.
    View in: PubMed
    Score: 0.016
  34. Xu W, Osei-Prempeh G, Lema C, Davis Oldham E, Aguilera RJ, Parkin S, Rankin SE, Knutson BL, Lehmler HJ. Synthesis, thermal properties, and cytotoxicity evaluation of hydrocarbon and fluorocarbon alkyl ?-D-xylopyranoside surfactants. Carbohydr Res. 2012 Feb 15; 349:12-23.
    View in: PubMed
    Score: 0.015
Connection Strength

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