Bone Morphogenetic Protein 2

"Bone Morphogenetic Protein 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A potent osteoinductive protein that plays a critical role in the differentiation of osteoprogenitor cells into OSTEOBLASTS.

Descriptor ID	D055396
MeSH Number(s)	D12.644.276.954.200.200 D12.776.467.942.200.200 D23.529.942.200.200
Concept/Terms	Bone Morphogenetic Protein 2 Bone Morphogenetic Protein 2

Below are MeSH descriptors whose meaning is more general than "Bone Morphogenetic Protein 2".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
TGF-beta Superfamily Proteins [D12.644.276.954]
Bone Morphogenetic Proteins [D12.644.276.954.200]
Bone Morphogenetic Protein 2 [D12.644.276.954.200.200]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
TGF-beta Superfamily Proteins [D12.776.467.942]
Bone Morphogenetic Proteins [D12.776.467.942.200]
Bone Morphogenetic Protein 2 [D12.776.467.942.200.200]
Biological Factors [D23]
Intercellular Signaling Peptides and Proteins [D23.529]
TGF-beta Superfamily Proteins [D23.529.942]
Bone Morphogenetic Proteins [D23.529.942.200]
Bone Morphogenetic Protein 2 [D23.529.942.200.200]

Below are MeSH descriptors whose meaning is related to "Bone Morphogenetic Protein 2".

Below are MeSH descriptors whose meaning is more specific than "Bone Morphogenetic Protein 2".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Bone Morphogenetic Protein 2" by people in this website by year, and whether "Bone Morphogenetic Protein 2" was a major or minor topic of these publications.

Bar chart showing 12 publications over 7 distinct years, with a maximum of 3 publications in 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2003	0	1	1
2007	0	2	2
2009	1	0	1
2011	2	0	2
2012	2	0	2
2013	2	1	3
2019	0	1	1

Below are the most recent publications written about "Bone Morphogenetic Protein 2" by people in Profiles.

Mann V, Grimm D, Corydon TJ, Kr?ger M, Wehland M, Riwaldt S, Sahana J, Kopp S, Bauer J, Reseland JE, Infanger M, Mari Lian A, Okoro E, Sundaresan A. Changes in Human Foetal Osteoblasts Exposed to the Random Positioning Machine and Bone Construct Tissue Engineering. Int J Mol Sci. 2019 Mar 18; 20(6).

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Carragee EJ, Chu G, Rohatgi R, Hurwitz EL, Weiner BK, Yoon ST, Comer G, Kopjar B. Cancer risk after use of recombinant bone morphogenetic protein-2 for spinal arthrodesis. J Bone Joint Surg Am. 2013 Sep 04; 95(17):1537-45.

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Weiner BK, Hurwitz EL, Schoene ML, Carragee EJ. Moving forward after YODA. Spine J. 2013 Sep; 13(9):995-7.

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Som A, Xiao L, Zhu R, Guo CC, Xiao L, Rao P, Efstathiou E, Matin A, Tu SM. Clinically atypical seminomas with yolk sac tumor features. Can J Urol. 2013 Aug; 20(4):6860-7.

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Comer GC, Smith MW, Hurwitz EL, Mitsunaga KA, Kessler R, Carragee EJ. Retrograde ejaculation after anterior lumbar interbody fusion with and without bone morphogenetic protein-2 augmentation: a 10-year cohort controlled study. Spine J. 2012 Oct; 12(10):881-90.

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Carragee EJ, Baker RM, Benzel EC, Bigos SJ, Cheng I, Corbin TP, Deyo RA, Hurwitz EL, Jarvik JG, Kang JD, Lurie JD, Mroz TE, Oner FC, Peul WC, Rainville J, Ratliff JK, Rihn JA, Rothman DJ, Schoene ML, Spengler DM, Weiner BK. A biologic without guidelines: the YODA project and the future of bone morphogenetic protein-2 research. Spine J. 2012 Oct; 12(10):877-80.

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Carragee EJ, Hurwitz EL, Weiner BK. A critical review of recombinant human bone morphogenetic protein-2 trials in spinal surgery: emerging safety concerns and lessons learned. Spine J. 2011 Jun; 11(6):471-91.

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Carragee EJ, Mitsunaga KA, Hurwitz EL, Scuderi GJ. Retrograde ejaculation after anterior lumbar interbody fusion using rhBMP-2: a cohort controlled study. Spine J. 2011 Jun; 11(6):511-6.

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Graham TR, Odero-Marah VA, Chung LW, Agrawal KC, Davis R, Abdel-Mageed AB. PI3K/Akt-dependent transcriptional regulation and activation of BMP-2-Smad signaling by NF-kappaB in metastatic prostate cancer cells. Prostate. 2009 Feb 01; 69(2):168-80.

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Mizuno N, Shiba H, Xu WP, Inui T, Fujita T, Kajiya M, Takeda K, Hasegawa N, Kawaguchi H, Kurihara H. Effect of neurotrophins on differentiation, calcification and proliferation in cultures of human pulp cells. Cell Biol Int. 2007 Dec; 31(12):1462-9.

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