"Integrin alpha5" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
This integrin alpha subunit combines with INTEGRIN BETA1 to form a receptor (INTEGRIN ALPHA5BETA1) that binds FIBRONECTIN and LAMININ. It undergoes posttranslational cleavage into a heavy and a light chain that are connected by disulfide bonds.
| Descriptor ID |
D039482
|
| MeSH Number(s) |
D12.776.543.750.705.408.100.500
|
| Concept/Terms |
Integrin alpha5- Integrin alpha5
- alpha5, Integrin
- alpha(5) Integrin
- alpha5 Integrin
- Integrin, alpha5
- VLA-5 alpha Chain
- VLA 5 alpha Chain
- alpha Chain, VLA-5
- CD49e Antigens
- Platelet Glycoprotein Ic
- Glycoprotein Ic, Platelet
- Ic, Platelet Glycoprotein
- Integrin alphaF
- alphaF, Integrin
- CD49e Antigen
- Antigen, CD49e
- Antigens, CD49e
|
Below are MeSH descriptors whose meaning is more general than "Integrin alpha5".
Below are MeSH descriptors whose meaning is more specific than "Integrin alpha5".
This graph shows the total number of publications written about "Integrin alpha5" by people in this website by year, and whether "Integrin alpha5" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Integrin alpha5" by people in Profiles.
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Zhang L, Shimizu D, Killeen JL, Honda SA, Lu D, Stanoyevitch A, Lin F, Wang B, Monuki ES, Carbone M. Serous carcinomatous component championed by heparin-binding EGF-like growth factor (HB-EGF) predisposing to metastasis and recurrence in stage I uterine malignant mixed mullerian tumor. Hum Pathol. 2016 07; 53:159-67.
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Neal CL, Mckeithen D, Odero-Marah VA. Snail negatively regulates cell adhesion to extracellular matrix and integrin expression via the MAPK pathway in prostate cancer cells. Cell Adh Migr. 2011 May-Jun; 5(3):249-57.