"Clostridium difficile" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A common inhabitant of the colon flora in human infants and sometimes in adults. It produces a toxin that causes pseudomembranous enterocolitis (ENTEROCOLITIS, PSEUDOMEMBRANOUS) in patients receiving antibiotic therapy.
Descriptor ID |
D016360
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MeSH Number(s) |
B03.300.390.400.200.250 B03.353.625.375.500.250 B03.510.415.400.200.250
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Clostridium difficile".
Below are MeSH descriptors whose meaning is more specific than "Clostridium difficile".
This graph shows the total number of publications written about "Clostridium difficile" by people in this website by year, and whether "Clostridium difficile" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2006 | 0 | 1 | 1 |
2007 | 1 | 0 | 1 |
2014 | 1 | 0 | 1 |
2016 | 2 | 1 | 3 |
2017 | 0 | 1 | 1 |
2018 | 0 | 1 | 1 |
2019 | 3 | 0 | 3 |
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Below are the most recent publications written about "Clostridium difficile" by people in Profiles.
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Saleh MM, Petri WA. Type 3 Immunity during Clostridioides difficile Infection: Too Much of a Good Thing? Infect Immun. 2019 12 17; 88(1).
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Saleh MM, Frisbee AL, Leslie JL, Buonomo EL, Cowardin CA, Ma JZ, Simpson ME, Scully KW, Abhyankar MM, Petri WA. Colitis-Induced Th17 Cells Increase the Risk for Severe Subsequent Clostridium difficile Infection. . 2019 May 08; 25(5):756-765.e5.
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Stone NE, Nunnally AE, Jimenez V, Cope EK, Sahl JW, Sheridan K, Hornstra HM, Vinocur J, Settles EW, Headley KC, Williamson CHD, Rideout JR, Bolyen E, Caporaso JG, Terriquez J, Monroy FP, Busch JD, Keim P, Wagner DM. Domestic canines do not display evidence of gut microbial dysbiosis in the presence of Clostridioides (Clostridium) difficile, despite cellular susceptibility to its toxins. Anaerobe. 2019 Aug; 58:53-72.
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Bui LN, Swan JT, Shirkey BA, Olsen RJ, Long SW, Graviss EA. Chlorhexidine bathing and Clostridium difficile infection in a surgical intensive care unit. J Surg Res. 2018 08; 228:107-111.
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Yoshikawa TT, Norman DC. Geriatric Infectious Diseases: Current Concepts on Diagnosis and Management. J Am Geriatr Soc. 2017 Mar; 65(3):631-641.
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Buonomo EL, Cowardin CA, Wilson MG, Saleh MM, Pramoonjago P, Petri WA. Microbiota-Regulated IL-25 Increases Eosinophil Number to Provide Protection during Clostridium difficile Infection. Cell Rep. 2016 07 12; 16(2):432-443.
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Andersson JA, Fitts EC, Kirtley ML, Ponnusamy D, Peniche AG, Dann SM, Motin VL, Chauhan S, Rosenzweig JA, Sha J, Chopra AK. New Role for FDA-Approved Drugs in Combating Antibiotic-Resistant Bacteria. Antimicrob Agents Chemother. 2016 06; 60(6):3717-29.
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White MB, Rajagopalan S, Yoshikawa TT. Infectious Diarrhea: Norovirus and Clostridium difficile in Older Adults. Clin Geriatr Med. 2016 08; 32(3):509-22.
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Tsutsumi LS, Owusu YB, Hurdle JG, Sun D. Progress in the discovery of treatments for C. difficile infection: A clinical and medicinal chemistry review. Curr Top Med Chem. 2014; 14(1):152-75.
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Zoutman DE, Ford BD. A comparison of infection control program resources, activities, and antibiotic resistant organism rates in Canadian acute care hospitals in 1999 and 2005: pre- and post-severe acute respiratory syndrome. Am J Infect Control. 2008 Dec; 36(10):711-7.