"Oligonucleotide Probes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Synthetic or natural oligonucleotides used in hybridization studies in order to identify and study specific nucleic acid fragments, e.g., DNA segments near or within a specific gene locus or gene. The probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the probe include the radioisotope labels 32P and 125I and the chemical label biotin.
| Descriptor ID |
D015345
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| MeSH Number(s) |
D13.444.600.601 D27.505.259.750.600.650 D27.720.470.530.600.650
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Oligonucleotide Probes".
Below are MeSH descriptors whose meaning is more specific than "Oligonucleotide Probes".
This graph shows the total number of publications written about "Oligonucleotide Probes" by people in this website by year, and whether "Oligonucleotide Probes" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 0 | 2 | 2 |
| 1996 | 0 | 4 | 4 |
| 1997 | 0 | 1 | 1 |
| 1998 | 1 | 1 | 2 |
| 2008 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Oligonucleotide Probes" by people in Profiles.
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Bayer LV, Omar OS, Bratu DP, Catrina IE. PinMol: Python application for designing molecular beacons for live cell imaging of endogenous mRNAs. RNA. 2019 03; 25(3):305-318.
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Jackson SR, Wong AC, Travis AR, Catrina IE, Bratu DP, Wright DW, Jayagopal A. Applications of Hairpin DNA-Functionalized Gold Nanoparticles for Imaging mRNA in Living Cells. Methods Enzymol. 2016; 572:87-103.
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Bratu DP, Catrina IE, Marras SA. Tiny molecular beacons for in vivo mRNA detection. Methods Mol Biol. 2011; 714:141-57.
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Villablanca A, Karhanek M, Caramuta S, Yu H, Jejelowo O, Webb CD, Pourmand N. Suspension bead array branch migration displacement assay for rapid STR analysis. Electrophoresis. 2008 Oct; 29(19):4109-14.
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Tyagi S, Bratu DP, Kramer FR. Multicolor molecular beacons for allele discrimination. Nat Biotechnol. 1998 Jan; 16(1):49-53.
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Hines MD, Radomska HS, Eckhardt LA. Transcription factor effects on chromosome constitution of cell hybrids. Cytogenet Cell Genet. 1998; 83(1-2):64-72.
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Das SK, Beg O, Mukherjee S. Partial characterization of guinea pig cholinephosphotransferase cDNA. Biochem Biophys Res Commun. 1997 Dec 18; 241(2):504-8.
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Zhang Y, Angulo JA. Contrasting effects of repeated treatment vs. withdrawal of methamphetamine on tyrosine hydroxylase messenger RNA levels in the ventral tegmental area and substantia nigra zona compacta of the rat brain. Synapse. 1996 Nov; 24(3):218-23.
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Small MB, Hubbard K, Pardinas JR, Marcus AM, Dhanaraj SN, Sethi KA. Maintenance of telomeres in SV40-transformed pre-immortal and immortal human fibroblasts. J Cell Physiol. 1996 Sep; 168(3):727-36.
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Jarrett HW. Hybrid selection with cDNA-silica. J Chromatogr A. 1996 Aug 23; 742(1-2):87-94.