"Diphosphonates" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Organic compounds which contain P-C-P bonds, where P stands for phosphonates or phosphonic acids. These compounds affect calcium metabolism. They inhibit ectopic calcification and slow down bone resorption and bone turnover. Technetium complexes of diphosphonates have been used successfully as bone scanning agents.
Descriptor ID |
D004164
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MeSH Number(s) |
D02.705.429.500
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Diphosphonates".
Below are MeSH descriptors whose meaning is more specific than "Diphosphonates".
This graph shows the total number of publications written about "Diphosphonates" by people in this website by year, and whether "Diphosphonates" was a major or minor topic of these publications.
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click here.
Year | Major Topic | Minor Topic | Total |
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2005 | 0 | 1 | 1 |
2007 | 0 | 1 | 1 |
2011 | 1 | 0 | 1 |
2012 | 0 | 1 | 1 |
2013 | 0 | 1 | 1 |
2014 | 1 | 3 | 4 |
2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Diphosphonates" by people in Profiles.
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Ferguson S, Feudjo Tepie M, Taylor A, Roddam A, Critchlow C, Iqbal M, Spangler L, Bayly J. The impact of persistence with bisphosphonates on health resource utilization and fracture risk in the UK: a study of patient records from the UK Clinical Practice Research Datalink. J Eval Clin Pract. 2016 Feb; 22(1):31-39.
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Li L, Roddam A, Ferguson S, Feudjo-Tepie M, Taylor A, Jick S. Switch patterns of osteoporosis medication and its impact on persistence among postmenopausal women in the U.K. General Practice Research Database. Menopause. 2014 Oct; 21(10):1106-13.
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Gonzalez-Villasana V, Rodriguez-Aguayo C, Arumugam T, Cruz-Monserrate Z, Fuentes-Mattei E, Deng D, Hwang RF, Wang H, Ivan C, Garza RJ, Cohen E, Gao H, Armaiz-Pena GN, Del C Monroig-Bosque P, Philip B, Rashed MH, Aslan B, Erdogan MA, Gutierrez-Puente Y, Ozpolat B, Reuben JM, Sood AK, Logsdon C, Lopez-Berestein G. Bisphosphonates inhibit stellate cell activity and enhance antitumor effects of nanoparticle albumin-bound paclitaxel in pancreatic ductal adenocarcinoma. Mol Cancer Ther. 2014 Nov; 13(11):2583-94.
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Uyanne J, Calhoun CC, Le AD. Antiresorptive drug-related osteonecrosis of the jaw. Dent Clin North Am. 2014 Apr; 58(2):369-84.
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D?az-Correa LM, Ram?rez-Garc?a LM, Castro-Santana LE, Vil? LM. Osteoporosis knowledge in patients with a first fragility fracture in Puerto Rico. Bol Asoc Med P R. 2014; 106(1):6-10.
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Costa-Reis P, Sullivan KE. Chronic recurrent multifocal osteomyelitis. J Clin Immunol. 2013 Aug; 33(6):1043-56.
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Li L, Roddam A, Gitlin M, Taylor A, Shepherd S, Shearer A, Jick S. Persistence with osteoporosis medications among postmenopausal women in the UK General Practice Research Database. Menopause. 2012 Jan; 19(1):33-40.
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L?pez-L?pez L, Vil? LM. Atypical subtrochanteric fractures associated with long-term use of bisphosphonates. P R Health Sci J. 2011 Dec; 30(4):211.
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Wilkins CH. Osteoporosis screening and risk management. Clin Interv Aging. 2007; 2(3):389-94.
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Wilkins CH, Birge SJ. Prevention of osteoporotic fractures in the elderly. Am J Med. 2005 Nov; 118(11):1190-5.