Benzo(a)pyrene

"Benzo(a)pyrene" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.

Descriptor ID	D001564
MeSH Number(s)	D02.455.426.559.847.799.306.300 D04.615.799.306.300
Concept/Terms	Benzo(a)pyrene Benzo(a)pyrene 3,4-Benzpyrene 3,4 Benzpyrene 3,4-Benzopyrene 3,4 Benzopyrene

Below are MeSH descriptors whose meaning is more general than "Benzo(a)pyrene".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Hydrocarbons [D02.455]
Hydrocarbons, Cyclic [D02.455.426]
Hydrocarbons, Aromatic [D02.455.426.559]
Polycyclic Aromatic Hydrocarbons [D02.455.426.559.847]
Pyrenes [D02.455.426.559.847.799]
Benzopyrenes [D02.455.426.559.847.799.306]
Benzo(a)pyrene [D02.455.426.559.847.799.306.300]
Polycyclic Compounds [D04]
Polycyclic Aromatic Hydrocarbons [D04.615]
Pyrenes [D04.615.799]
Benzopyrenes [D04.615.799.306]
Benzo(a)pyrene [D04.615.799.306.300]

Below are MeSH descriptors whose meaning is related to "Benzo(a)pyrene".

Below are MeSH descriptors whose meaning is more specific than "Benzo(a)pyrene".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Benzo(a)pyrene" by people in this website by year, and whether "Benzo(a)pyrene" was a major or minor topic of these publications.

Bar chart showing 67 publications over 22 distinct years, with a maximum of 9 publications in 2012

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	0	1
1999	1	0	1
2000	2	0	2
2001	3	0	3
2002	2	0	2
2003	4	1	5
2004	2	0	2
2005	3	0	3
2006	3	0	3
2007	5	0	5
2008	4	1	5
2009	3	1	4
2010	2	1	3
2011	2	0	2
2012	8	1	9
2013	3	0	3
2014	2	0	2
2015	4	1	5
2016	2	2	4
2017	0	1	1
2018	1	0	1
2020	1	0	1

Below are the most recent publications written about "Benzo(a)pyrene" by people in Profiles.

Harris KJ, Subbiah S, Tabatabai M, Archibong AE, Singh KP, Anderson TA, Adunyah SE, Ramesh A. Pressurized liquid extraction followed by liquid chromatography coupled to a fluorescence detector and atmospheric pressure chemical ionization mass spectrometry for the determination of benzo(a)pyrene metabolites in liver tissue of an animal model of colon cancer. J Chromatogr A. 2020 Jul 05; 1622:461126.

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Huderson AC, Rekha Devi PV, Niaz MS, Adunyah SE, Ramesh A. Alteration of benzo(a)pyrene biotransformation by resveratrol in ApcMin/+ mouse model of colon carcinogenesis. Invest New Drugs. 2019 04; 37(2):238-251.

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Jin F, Thaiparambil J, Donepudi SR, Vantaku V, Piyarathna DWB, Maity S, Krishnapuram R, Putluri V, Gu F, Purwaha P, Bhowmik SK, Ambati CR, von Rundstedt FC, Roghmann F, Berg S, Noldus J, Rajapakshe K, Gödde D, Roth S, Störkel S, Degener S, Michailidis G, Kaipparettu BA, Karanam B, Terris MK, Kavuri SM, Lerner SP, Kheradmand F, Coarfa C, Sreekumar A, Lotan Y, El-Zein R, Putluri N. Tobacco-Specific Carcinogens Induce Hypermethylation, DNA Adducts, and DNA Damage in Bladder Cancer. Cancer Prev Res (Phila). 2017 Oct; 10(10):588-597.

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Yang F, Yang H, Ramesh A, Goodwin JS, Okoro EU, Guo Z. Overexpression of Catalase Enhances Benzo(a)pyrene Detoxification in Endothelial Microsomes. PLoS One. 2016; 11(9):e0162561.

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Hubbard TD, Murray IA, Bisson WH, Sullivan AP, Sebastian A, Perry GH, Jablonski NG, Perdew GH. Divergent Ah Receptor Ligand Selectivity during Hominin Evolution. Mol Biol Evol. 2016 10; 33(10):2648-58.

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Harris KL, Pulliam SR, Okoro E, Guo Z, Washington MK, Adunyah SE, Amos-Landgraf JM, Ramesh A. Western diet enhances benzo(a)pyrene-induced colon tumorigenesis in a polyposis in rat coli (PIRC) rat model of colon cancer. Oncotarget. 2016 May 17; 7(20):28947-60.

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Clark RS, Pellom ST, Booker B, Ramesh A, Zhang T, Shanker A, Maguire M, Juarez PD, Patricia MJ, Langston MA, Lichtveld MY, Hood DB. Validation of research trajectory 1 of an Exposome framework: Exposure to benzo(a)pyrene confers enhanced susceptibility to bacterial infection. Environ Res. 2016 Apr; 146:173-84.

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Ramesh A, Prins PA, Perati PR, Rekhadevi PV, Sampson UK. Metabolism of benzo(a)pyrene by aortic subcellular fractions in the setting of abdominal aortic aneurysms. Mol Cell Biochem. 2016 Jan; 411(1-2):383-91.

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Banks LD, Amoah P, Niaz MS, Washington MK, Adunyah SE, Ramesh A. Olive oil prevents benzo(a)pyrene [B(a)P]-induced colon carcinogenesis through altered B(a)P metabolism and decreased oxidative damage in Apc(Min) mouse model. J Nutr Biochem. 2016 Feb; 28:37-50.

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McCallister MM, Li Z, Zhang T, Ramesh A, Clark RS, Maguire M, Hutsell B, Newland MC, Hood DB. Revealing Behavioral Learning Deficit Phenotypes Subsequent to In Utero Exposure to Benzo(a)pyrene. Toxicol Sci. 2016 Jan; 149(1):42-54.

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