Antidepressive Agents, Tricyclic
"Antidepressive Agents, Tricyclic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Substances that contain a fused three-ring moiety and are used in the treatment of depression. These drugs block the uptake of norepinephrine and serotonin into axon terminals and may block some subtypes of serotonin, adrenergic, and histamine receptors. However the mechanism of their antidepressant effects is not clear because the therapeutic effects usually take weeks to develop and may reflect compensatory changes in the central nervous system.
| Descriptor ID |
D000929
|
| MeSH Number(s) |
D27.505.954.427.700.122.055
|
| Concept/Terms |
Antidepressive Agents, Tricyclic- Antidepressive Agents, Tricyclic
- Tricyclic Antidepressive Agents
- Agents, Tricyclic Antidepressive
- Antidepressant Drugs, Tricyclic
- Drugs, Tricyclic Antidepressant
- Tricyclic Antidepressant Drugs
- Antidepressants, Tricyclic
- Tricyclic Antidepressants
|
Below are MeSH descriptors whose meaning is more general than "Antidepressive Agents, Tricyclic".
Below are MeSH descriptors whose meaning is more specific than "Antidepressive Agents, Tricyclic".
This graph shows the total number of publications written about "Antidepressive Agents, Tricyclic" by people in this website by year, and whether "Antidepressive Agents, Tricyclic" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 1 | 2 |
| 1995 | 1 | 0 | 1 |
| 1997 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 2 | 2 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Antidepressive Agents, Tricyclic" by people in Profiles.
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Getachew B, Hauser SR, Csoka AB, Taylor RE, Tizabi Y. Role of cortical alpha-2 adrenoceptors in alcohol withdrawal-induced depression and tricyclic antidepressants. Drug Alcohol Depend. 2017 06 01; 175:133-139.
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Serafine KM, Riley AL. Possible role of norepinephrine in cocaine-induced conditioned taste aversions. Pharmacol Biochem Behav. 2009 Mar; 92(1):111-6.
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Mellman T, Lydiard RB. Posttraumatic stress disorder: characteristics and treatment. J Clin Psychiatry. 2008 Jan; 69(1):e2.
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Piletz J, Baker R, Halaris A. Platelet imidazoline receptors as state marker of depressive symptomatology. J Psychiatr Res. 2008 Jan; 42(1):41-9.
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Nyanda AM, Nunes MG, Ramesh A. A simple high-performance liquid chromatography method for the quantitation of tricyclic antidepressant drugs in human plasma or serum. J Toxicol Clin Toxicol. 2000; 38(6):631-6.
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Zhu H, Halaris A, Piletz JE. Chronic imipramine treatment downregulates IR1-imidazoline receptors in rat brainstem. Life Sci. 1997; 61(19):1973-83.
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Frankfurt M, McKittrick CR, McEwen BS, Luine VN. Tianeptine treatment induces regionally specific changes in monoamines. Brain Res. 1995 Oct 23; 696(1-2):1-6.
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Luine V, Villegas M, Martinez C, McEwen BS. Stress-dependent impairments of spatial memory. Role of 5-HT. Ann N Y Acad Sci. 1994 Nov 30; 746:403-4.
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Luine V, Villegas M, Martinez C, McEwen BS. Repeated stress causes reversible impairments of spatial memory performance. Brain Res. 1994 Mar 07; 639(1):167-70.
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Csiszar K, Molnar J. Mechanism of action of tricyclic drugs on Escherichia coli and Yersinia enterocolitica plasmid maintenance and replication. Anticancer Res. 1992 Nov-Dec; 12(6B):2267-72.