Cellular response to Trypanosoma cruzi infection induces secretion of defensin a-1, which damages the flagellum, neutralizes trypanosome motility, and inhibits infection.

Johnson CA, Rachakonda G, Kleshchenko YY, Nde PN, Madison MN, Pratap S, Cardenas TC, Taylor C, Lima MF, Villalta F. Cellular response to Trypanosoma cruzi infection induces secretion of defensin a-1, which damages the flagellum, neutralizes trypanosome motility, and inhibits infection. Infect Immun. 2013 Nov; 81(11):4139-48.

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subject areas

alpha-Defensins
Cell Membrane
Epithelial Cells
Flagella
HCT116 Cells
Humans
Locomotion
Trypanosoma cruzi

authors with profiles

Fernando Villalta
PIUS NDE
Siddharth Pratap

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