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Connection

Mitchell Schaffler to Insulin-Like Growth Factor I

This is a "connection" page, showing publications Mitchell Schaffler has written about Insulin-Like Growth Factor I.
  1. Poudel SB, Ruff RR, He Z, Dixit M, Yildirim G, Jayarathne H, Manchanayake DH, Basta-Pljakic J, Duran-Ortiz S, Schaffler MB, Kopchick JJ, Sadagurski M, Yakar S. The impact of inactivation of the GH/IGF axis during aging on healthspan. Geroscience. 2025 Jun; 47(3):3027-3042.
    View in: PubMed
    Score: 0.216
  2. Dixit M, Louis LD, Basta-Pljakic J, Yildirim G, Poudel SB, Kumararaja F, List EO, Duran SO, Kopchick JJ, Ruff RR, Schaffler MB, Yakar S. Lifelong Excess in GH Elicits Sexually Dimorphic Effects on Skeletal Morphology and Bone Mechanical Properties. J Bone Miner Res. 2022 11; 37(11):2201-2214.
    View in: PubMed
    Score: 0.186
  3. Liu Z, Solesio ME, Schaffler MB, Frikha-Benayed D, Rosen CJ, Werner H, Kopchick JJ, Pavlov EV, Abramov AY, Yakar S. Mitochondrial Function Is Compromised in Cortical Bone Osteocytes of Long-Lived Growth Hormone Receptor Null Mice. J Bone Miner Res. 2019 01; 34(1):106-122.
    View in: PubMed
    Score: 0.141
  4. Liu Z, Han T, Werner H, Rosen CJ, Schaffler MB, Yakar S. Reduced Serum IGF-1 Associated With Hepatic Osteodystrophy Is a Main Determinant of Low Cortical but Not Trabecular Bone Mass. J Bone Miner Res. 2018 01; 33(1):123-136.
    View in: PubMed
    Score: 0.133
  5. Gong Z, Kennedy O, Sun H, Wu Y, Williams GA, Klein L, Cardoso L, Matheny RW, Hubbard GB, Ikeno Y, Farrar RP, Schaffler MB, Adamo ML, Muzumdar RH, Yakar S. Reductions in serum IGF-1 during aging impair health span. Aging Cell. 2014 Jun; 13(3):408-18.
    View in: PubMed
    Score: 0.101
  6. Wu Y, Sun H, Basta-Pljakic J, Cardoso L, Kennedy OD, Jasper H, Domen? H, Karabatas L, Guida C, Schaffler MB, Rosen CJ, Yakar S. Serum IGF-1 is insufficient to restore skeletal size in the total absence of the growth hormone receptor. J Bone Miner Res. 2013 Jul; 28(7):1575-86.
    View in: PubMed
    Score: 0.098
  7. Courtland HW, Kennedy OD, Wu Y, Gao Y, Sun H, Schaffler MB, Yakar S. Low levels of plasma IGF-1 inhibit intracortical bone remodeling during aging. Age (Dordr). 2013 Oct; 35(5):1691-703.
    View in: PubMed
    Score: 0.093
  8. Fritton JC, Emerton KB, Sun H, Kawashima Y, Mejia W, Wu Y, Rosen CJ, Panus D, Bouxsein M, Majeska RJ, Schaffler MB, Yakar S. Growth hormone protects against ovariectomy-induced bone loss in states of low circulating insulin-like growth factor (IGF-1). J Bone Miner Res. 2010 Feb; 25(2):235-46.
    View in: PubMed
    Score: 0.077
  9. Yakar S, Rosen CJ, Bouxsein ML, Sun H, Mejia W, Kawashima Y, Wu Y, Emerton K, Williams V, Jepsen K, Schaffler MB, Majeska RJ, Gavrilova O, Gutierrez M, Hwang D, Pennisi P, Frystyk J, Boisclair Y, Pintar J, Jasper H, Domene H, Cohen P, Clemmons D, LeRoith D. Serum complexes of insulin-like growth factor-1 modulate skeletal integrity and carbohydrate metabolism. FASEB J. 2009 Mar; 23(3):709-19.
    View in: PubMed
    Score: 0.071
  10. Liu Z, Han T, Fishman S, Butler J, Zimmermann T, Tremblay F, Harbison C, Agrawal N, Kopchick JJ, Schaffler MB, Yakar S. Ablation of Hepatic Production of the Acid-Labile Subunit in Bovine-GH Transgenic Mice: Effects on Organ and Skeletal Growth. Endocrinology. 2017 08 01; 158(8):2556-2571.
    View in: PubMed
    Score: 0.033
  11. Kennedy OD, Sun H, Wu Y, Courtland HW, Williams GA, Cardoso L, Basta-Pljakic J, Schaffler MB, Yakar S. Skeletal response of male mice to anabolic hormone therapy in the absence of the Igfals gene. Endocrinology. 2014 Mar; 155(3):987-99.
    View in: PubMed
    Score: 0.025
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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