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Jon-Paul Bingham, PhD

Faculty RankProfessor
InstitutionUniversity of Hawaii
AddressSchool of Life Sciences
University of Hawaii at Manoa
1800 East-West Road
Honolulu HI
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Laczko R, Chang A, Watanabe L, Petelo M, Kahaleua K, Bingham JP, Csiszar K. Anti-inflammatory activities of Waltheria indica extracts by modulating expression of IL-1B, TNF-a, TNFRII and NF-?B in human macrophages. Inflammopharmacology. 2020 Apr; 28(2):525-540. PMID: 31686273.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    2. Oeser SG, Bingham JP, Collier AC. Regulation of Hepatic UGT2B15 by Methylation in Adults of Asian Descent. Pharmaceutics. 2018 Jan 07; 10(1). PMID: 29316660.
    3. Zhang RY, Thapa P, Espiritu MJ, Menon V, Bingham JP. From nature to creation: Going around in circles, the art of peptide cyclization. Bioorg Med Chem. 2018 03 15; 26(6):1135-1150. PMID: 29295762.
      Citations: 3     Fields:    Translation:AnimalsCells
    4. Thapa P, Cabalteja CC, Philips EE, Espiritu MJ, Peigneur S, Mille BG, Tytgat J, Cummins TR, Bingham JP. t-boc synthesis of huwentoxin-i through native chemical ligation incorporating a trifluoromethanesulfonic acid cleavage strategy. Biopolymers. 2016 Sep; 106(5):737-45. PMID: 27271997.
      Citations:    Fields:    
    5. Halford ZA, Yu PY, Likeman RK, Hawley-Molloy JS, Thomas C, Bingham JP. Cone shell envenomation: epidemiology, pharmacology and medical care. Diving Hyperb Med. 2015 Sep; 45(3):200-7. PMID: 26415072.
      Citations: 2     Fields:    Translation:HumansAnimals
    6. Thapa P, Zhang RY, Menon V, Bingham JP. Native chemical ligation: a boon to peptide chemistry. Molecules. 2014 Sep 12; 19(9):14461-83. PMID: 25221869.
      Citations: 11     Fields:    Translation:Humans
    7. Thapa P, Espiritu MJ, Cabalteja CC, Bingham JP. Conotoxins and their regulatory considerations. Regul Toxicol Pharmacol. 2014 Oct; 70(1):197-202. PMID: 25013992.
      Citations: 3     Fields:    Translation:HumansAnimals
    8. Yafuso JT, Negi VS, Bingham JP, Borthakur D. An O-acetylserine (thiol) lyase from Leucaena leucocephala is a cysteine synthase but not a mimosine synthase. Appl Biochem Biotechnol. 2014 Jul; 173(5):1157-68. PMID: 24777760.
      Citations: 1     Fields:    Translation:AnimalsCells
    9. Espiritu MJ, Collier AC, Bingham JP. A 21st-century approach to age-old problems: the ascension of biologics in clinical therapeutics. Drug Discov Today. 2014 Aug; 19(8):1109-13. PMID: 24480607.
      Citations: 5     Fields:    Translation:HumansAnimals
    10. Takacs Z, Imredy JP, Bingham JP, Zhorov BS, Moczydlowski EG. Interaction of the BKCa channel gating ring with dendrotoxins. Channels (Austin). 2014; 8(5):421-32. PMID: 25483585.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    11. Negi VS, Bingham JP, Li QX, Borthakur D. A carbon-nitrogen lyase from Leucaena leucocephala catalyzes the first step of mimosine degradation. Plant Physiol. 2014 Feb; 164(2):922-34. PMID: 24351687.
      Citations: 4     Fields:    Translation:AnimalsCells
    12. Espiritu MJ, Cabalteja CC, Sugai CK, Bingham JP. Incorporation of post-translational modified amino acids as an approach to increase both chemical and biological diversity of conotoxins and conopeptides. Amino Acids. 2014 Jan; 46(1):125-51. PMID: 24221351.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    13. Bergeron ZL, Chun JB, Baker MR, Sandall DW, Peigneur S, Yu PY, Thapa P, Milisen JW, Tytgat J, Livett BG, Bingham JP. A 'conovenomic' analysis of the milked venom from the mollusk-hunting cone snail Conus textile--the pharmacological importance of post-translational modifications. Peptides. 2013 Nov; 49:145-58. PMID: 24055806.
      Citations: 3     Fields:    Translation:AnimalsCells
    14. Kapono CA, Thapa P, Cabalteja CC, Guendisch D, Collier AC, Bingham JP. Conotoxin truncation as a post-translational modification to increase the pharmacological diversity within the milked venom of Conus magus. Toxicon. 2013 Aug; 70:170-8. PMID: 23668937.
      Citations: 3     Fields:    Translation:AnimalsCells
    15. Negi VS, Bingham JP, Li QX, Borthakur D. midD-encoded 'rhizomimosinase' from Rhizobium sp. strain TAL1145 is a C-N lyase that catabolizes L-mimosine into 3-hydroxy-4-pyridone, pyruvate and ammonia. Amino Acids. 2013 Jun; 44(6):1537-47. PMID: 23462928.
      Citations: 2     Fields:    Translation:Cells
    16. Bergeron ZL, Bingham JP. Scorpion toxins specific for potassium (K+) channels: a historical overview of peptide bioengineering. Toxins (Basel). 2012 Nov 01; 4(11):1082-119. PMID: 23202307.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    17. Bingham JP, Andrews EA, Kiyabu SM, Cabalteja CC. Drugs from slugs. Part II--conopeptide bioengineering. Chem Biol Interact. 2012 Dec 05; 200(2-3):92-113. PMID: 23063744.
      Citations: 3     Fields:    Translation:Animals
    18. Bingham JP, Baker MR, Chun JB. Analysis of a cone snail's killer cocktail--the milked venom of Conus geographus. Toxicon. 2012 Nov; 60(6):1166-70. PMID: 22884604.
      Citations: 5     Fields:    Translation:AnimalsCells
    19. Chun JB, Baker MR, Kim DH, Leroy M, Toribo P, Bingham JP. Cone snail milked venom dynamics--a quantitative study of Conus purpurascens. Toxicon. 2012 Jul; 60(1):83-94. PMID: 22497788.
      Citations: 9     Fields:    Translation:AnimalsCells
    20. Bingham JP, Mitsunaga E, Bergeron ZL. Drugs from slugs--past, present and future perspectives of omega-conotoxin research. Chem Biol Interact. 2010 Jan 05; 183(1):1-18. PMID: 19800874.
      Citations: 19     Fields:    Translation:AnimalsCells
    21. Bingham JP, Chun JB, Ruzicka MR, Li QX, Tan ZY, Kaulin YA, Englebretsen DR, Moczydlowski EG. Synthesis of an iberiotoxin derivative by chemical ligation: a method for improved yields of cysteine-rich scorpion toxin peptides. Peptides. 2009 Jun; 30(6):1049-57. PMID: 19463736.
      Citations: 3     Fields:    Translation:HumansCells
    22. Xiao Y, Bingham JP, Zhu W, Moczydlowski E, Liang S, Cummins TR. Tarantula huwentoxin-IV inhibits neuronal sodium channels by binding to receptor site 4 and trapping the domain ii voltage sensor in the closed configuration. J Biol Chem. 2008 Oct 03; 283(40):27300-13. PMID: 18628201.
      Citations: 68     Fields:    Translation:HumansAnimalsCells
    23. Bingham JP, Bian S, Tan ZY, Takacs Z, Moczydlowski E. Synthesis of a biotin derivative of iberiotoxin: binding interactions with streptavidin and the BK Ca2+-activated K+ channel expressed in a human cell line. Bioconjug Chem. 2006 May-Jun; 17(3):689-99. PMID: 16704206.
      Citations: 6     Fields:    Translation:HumansCells
    24. Krishnan MN, Bingham JP, Lee SH, Trombley P, Moczydlowski E. Functional role and affinity of inorganic cations in stabilizing the tetrameric structure of the KcsA K+ channel. J Gen Physiol. 2005 Sep; 126(3):271-83. PMID: 16129774.
      Citations: 18     Fields:    Translation:Cells
    25. Bingham JP, Broxton NM, Livett BG, Down JG, Jones A, Moczydlowski EG. Optimizing the connectivity in disulfide-rich peptides: alpha-conotoxin SII as a case study. Anal Biochem. 2005 Mar 01; 338(1):48-61. PMID: 15707935.
      Citations: 2     Fields:    Translation:AnimalsCells
    26. Jakubowski JA, Keays DA, Kelley WP, Sandall DW, Bingham JP, Livett BG, Gayler KR, Sweedler JV. Determining sequences and post-translational modifications of novel conotoxins in Conus victoriae using cDNA sequencing and mass spectrometry. J Mass Spectrom. 2004 May; 39(5):548-57. PMID: 15170751.
      Citations: 18     Fields:    Translation:AnimalsCells
    27. Marshall J, Kelley WP, Rubakhin SS, Bingham JP, Sweedler JV, Gilly WF. Anatomical correlates of venom production in Conus californicus. Biol Bull. 2002 Aug; 203(1):27-41. PMID: 12200253.
      Citations: 17     Fields:    Translation:Animals
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    RCMI CC is supported by the National Institute on Minority Health and Health Disparities, National Institutes of Health (NIH), through Grant Number U24MD015970. The contents of this site are solely the responsibility of the authors and do not necessarily represent the official views of the NIH

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