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Marcus Cooke

Faculty RankProfessor
Address11200 SW 8th street
Academic Health Center 5
Miami FL 33199
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    Collapse Research 
    Collapse research activities and funding
    R15ES027196     (COOKE, MARCUS STANLEY)May 1, 2017 - Apr 30, 2020
    NIH/NIEHS
    Genomic instability, susceptibility to oxidative stress and cellular senescence
    Role: Principal Investigator

    R41ES030274     (ROSS, CHRISTOPHER)Feb 15, 2019 - Jan 31, 2020
    NIH/NIEHS
    AHTP-comet: development of an automated, high throughput comet assay system
    Role: Co-Principal Investigator

    R01ES030557     (COOKE, MARCUS STANLEY)Apr 1, 2019 - Dec 31, 2024
    NIH/NIEHS
    Urinary DNA Adductomics for the Assessment of Exposure to Cancer Risk Factors
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Gorini F, Scala G, Cooke MS, Majello B, Amente S. Towards a comprehensive view of 8-oxo-7,8-dihydro-2'-deoxyguanosine: Highlighting the intertwined roles of DNA damage and epigenetics in genomic instability. DNA Repair (Amst). 2020 Nov 26; 97:103027. PMID: 33285475.
      Citations:    
    2. Møller P, Azqueta A, Boutet-Robinet E, Koppen G, Bonassi S, Milic M, Gajski G, Costa S, Teixeira JP, Costa Pereira C, Dusinska M, Godschalk R, Brunborg G, Gutzkow KB, Giovannelli L, Cooke MS, Richling E, Laffon B, Valdiglesias V, Basaran N, Del Bo' C, Zegura B, Novak M, Stopper H, Vodicka P, Vodenkova S, de Andrade VM, Sramkova M, Gabelova A, Collins A, Langie SAS. Minimum Information for Reporting on the Comet Assay (MIRCA): recommendations for describing comet assay procedures and results. Nat Protoc. 2020 Dec; 15(12):3817-3826. PMID: 33106678.
      Citations:    Fields:    
    3. Burke SL, Cobb J, Agarwal R, Maddux M, Cooke MS. How Robust is the Evidence for a Role of Oxidative Stress in Autism Spectrum Disorders and Intellectual Disabilities? J Autism Dev Disord. 2020 Sep 14. PMID: 32929662.
      Citations:    Fields:    
    4. Shih BB, Farrar MD, Vail A, Allan D, Chao MR, Hu CW, Jones GDD, Cooke MS, Rhodes LE. Influence of skin melanisation and ultraviolet radiation on biomarkers of systemic oxidative stress. Free Radic Biol Med. 2020 Nov 20; 160:40-46. PMID: 32768566.
      Citations:    Fields:    
    5. Guo J, Turesky RJ, Tarifa A, DeCaprio AP, Cooke MS, Walmsley SJ, Villalta PW. Development of a DNA Adductome Mass Spectral Database. Chem Res Toxicol. 2020 04 20; 33(4):852-854. PMID: 32223224.
      Citations:    Fields:    
    6. Karbaschi M, Ji Y, Abdulwahed AMS, Alohaly A, Bedoya JF, Burke SL, Boulos TM, Tempest HG, Cooke MS. Evaluation of the Major Steps in the Conventional Protocol for the Alkaline Comet Assay. Int J Mol Sci. 2019 Dec 02; 20(23). PMID: 31810189.
      Citations:    Fields:    Translation:HumansPHPublic Health
    7. Cooke MS, Hu CW, Chao MR. Editorial: Mass Spectrometry for Adductomic Analysis. Front Chem. 2019; 7:794. PMID: 31824925.
      Citations:    
    8. Samaranayake GJ, Troccoli CI, Zhang L, Huynh M, Jayaraj CJ, Ji D, McPherson L, Onishi Y, Nguyen DM, Robbins DJ, Karbaschi M, Cooke MS, Barrientos A, Kool ET, Rai P. The Existence of MTH1-independent 8-oxodGTPase Activity in Cancer Cells as a Compensatory Mechanism against On-target Effects of MTH1 Inhibitors. . 2020 02; 19(2):432-446. PMID: 31744893.
      Citations:    
    9. Hu CW, Chang YJ, Cooke MS, Chao MR. DNA Crosslinkomics: A Tool for the Comprehensive Assessment of Interstrand Crosslinks Using High Resolution Mass Spectrometry. Anal Chem. 2019 12 03; 91(23):15193-15203. PMID: 31670503.
      Citations: 1     Fields:    Translation:Animals
    10. Tenenbaum R, Agarwal R, Cooke MS, Agrawal MM, Maddux M, Burke SL. Utilization of Complementary and Alternative Therapies in Youth with Developmental Disabilities. Evid Based Complement Alternat Med. 2019; 2019:3630509. PMID: 31341491.
      Citations:    
    11. Ji Y, Karbaschi M, Cooke MS. Mycoplasma infection of cultured cells induces oxidative stress and attenuates cellular base excision repair activity. Mutat Res. 2019 09; 845:403054. PMID: 31561888.
      Citations: 1     Fields:    Translation:HumansCells
    12. Shih YM, Cooke MS, Pan CH, Chao MR, Hu CW. Clinical relevance of guanine-derived urinary biomarkers of oxidative stress, determined by LC-MS/MS. Redox Biol. 2019 01; 20:556-565. PMID: 30508700.
      Citations: 5     Fields:    Translation:Humans
    13. Cooke MS, Hu CW, Chang YJ, Chao MR. Urinary DNA adductomics - A novel approach for exposomics. Environ Int. 2018 12; 121(Pt 2):1033-1038. PMID: 30392940.
      Citations: 3     Fields:    Translation:HumansPHPublic Health
    14. Chao MR, Cooke MS, Kuo CY, Pan CH, Liu HH, Yang HJ, Chen SC, Chiang YC, Hu CW. Children are particularly vulnerable to environmental tobacco smoke exposure: Evidence from biomarkers of tobacco-specific nitrosamines, and oxidative stress. Environ Int. 2018 11; 120:238-245. PMID: 30103123.
      Citations: 8     Fields:    Translation:HumansAnimalsPHPublic Health
    15. Hu CW, Cooke MS, Chang YJ, Chao MR. Direct-acting DNA ethylating agents associated with tobacco use primarily originate from the tobacco itself, not combustion. J Hazard Mater. 2018 09 15; 358:397-404. PMID: 30005251.
      Citations: 1     Fields:    Translation:AnimalsPHPublic Health
    16. Chang YJ, Cooke MS, Hu CW, Chao MR. Novel approach to integrated DNA adductomics for the assessment of in vitro and in vivo environmental exposures. Arch Toxicol. 2018 08; 92(8):2665-2680. PMID: 29943112.
      Citations: 7     Fields:    Translation:AnimalsPHPublic Health
    17. Shih BB, Farrar MD, Cooke MS, Osman J, Langton AK, Kift R, Webb AR, Berry JL, Watson REB, Vail A, de Gruijl FR, Rhodes LE. Fractional Sunburn Threshold UVR Doses Generate Equivalent Vitamin D and DNA Damage in Skin Types I-VI but with Epidermal DNA Damage Gradient Correlated to Skin Darkness. J Invest Dermatol. 2018 10; 138(10):2244-2252. PMID: 29730334.
      Citations: 6     Fields:    Translation:Humans
    18. Kim G, Karbaschi M, Cooke M, Gaitas A. Light-based methods for whole blood bacterial inactivation enabled by a recirculating flow system. Photochem Photobiol. 2018 07; 94(4):744-751. PMID: 29418006.
      Citations: 1     Fields:    Translation:AnimalsCells
    19. Delinasios GJ, Karbaschi M, Cooke MS, Young AR. Author Correction: Vitamin E inhibits the UVAI induction of "light" and "dark" cyclobutane pyrimidine dimers, and oxidatively generated DNA damage, in keratinocytes. Sci Rep. 2018 Mar 19; 8(1):4998. PMID: 29555945.
      Citations:    Fields:    
    20. Delinasios GJ, Karbaschi M, Cooke MS, Young AR. Vitamin E inhibits the UVAI induction of "light" and "dark" cyclobutane pyrimidine dimers, and oxidatively generated DNA damage, in keratinocytes. Sci Rep. 2018 01 11; 8(1):423. PMID: 29323251.
      Citations: 7     Fields:    Translation:HumansCells
    21. Olinski R, Gackowski D, Cooke MS. Endogenously generated DNA nucleobase modifications source, and significance as possible biomarkers of malignant transformation risk, and role in anticancer therapy. Biochim Biophys Acta Rev Cancer. 2018 Jan; 1869(1):29-41. PMID: 29128527.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    22. Egea J, Fabregat I, Frapart YM, Ghezzi P, Görlach A, Kietzmann T, Kubaichuk K, Knaus UG, Lopez MG, Olaso-Gonzalez G, Petry A, Schulz R, Vina J, Winyard P, Abbas K, Ademowo OS, Afonso CB, Andreadou I, Antelmann H, Antunes F, Aslan M, Bachschmid MM, Barbosa RM, Belousov V, Berndt C, Bernlohr D, Bertrán E, Bindoli A, Bottari SP, Brito PM, Carrara G, Casas AI, Chatzi A, Chondrogianni N, Conrad M, Cooke MS, Costa JG, Cuadrado A, My-Chan Dang P, De Smet B, Debelec-Butuner B, Dias IHK, Dunn JD, Edson AJ, El Assar M, El-Benna J, Ferdinandy P, Fernandes AS, Fladmark KE, Förstermann U, Giniatullin R, Giricz Z, Görbe A, Griffiths H, Hampl V, Hanf A, Herget J, Hernansanz-Agustín P, Hillion M, Huang J, Ilikay S, Jansen-Dürr P, Jaquet V, Joles JA, Kalyanaraman B, Kaminskyy D, Karbaschi M, Kleanthous M, Klotz LO, Korac B, Korkmaz KS, Koziel R, Kracun D, Krause KH, Kren V, Krieg T, Laranjinha J, Lazou A, Li H, Martínez-Ruiz A, Matsui R, McBean GJ, Meredith SP, Messens J, Miguel V, Mikhed Y, Milisav I, Milkovic L, Miranda-Vizuete A, Mojovic M, Monsalve M, Mouthuy PA, Mulvey J, Münzel T, Muzykantov V, Nguyen ITN, Oelze M, Oliveira NG, Palmeira CM, Papaevgeniou N, Pavicevic A, Pedre B, Peyrot F, Phylactides M, Pircalabioru GG, Pitt AR, Poulsen HE, Prieto I, Rigobello MP, Robledinos-Antón N, Rodríguez-Mañas L, Rolo AP, Rousset F, Ruskovska T, Saraiva N, Sasson S, Schröder K, Semen K, Seredenina T, Shakirzyanova A, Smith GL, Soldati T, Sousa BC, Spickett CM, Stancic A, Stasia MJ, Steinbrenner H, Stepanic V, Steven S, Tokatlidis K, Tuncay E, Turan B, Ursini F, Vacek J, Vajnerova O, Valentová K, Van Breusegem F, Varisli L, Veal EA, Yalçin AS, Yelisyeyeva O, Žarkovic N, Zatloukalová M, Zielonka J, Touyz RM, Papapetropoulos A, Grune T, Lamas S, Schmidt HHHW, Di Lisa F, Daiber A. European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS). Redox Biol. 2017 10; 13:94-162. PMID: 28577489.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    23. Evans MD, Mistry V, Singh R, Gackowski D, Rózalski R, Siomek-Gorecka A, Phillips DH, Zuo J, Mullenders L, Pines A, Nakabeppu Y, Sakumi K, Sekiguchi M, Tsuzuki T, Bignami M, Olinski R, Cooke MS. Nucleotide excision repair of oxidised genomic DNA is not a source of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine. Free Radic Biol Med. 2016 10; 99:385-391. PMID: 27585947.
      Citations: 8     Fields:    Translation:AnimalsCells
    24. Rossner P, Orhan H, Koppen G, Sakai K, Santella RM, Ambroz A, Rossnerova A, Sram RJ, Ciganek M, Neca J, Arzuk E, Mutlu N, Cooke MS. Urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine analysis by an improved ELISA: An inter-laboratory comparison study. Free Radic Biol Med. 2016 06; 95:169-79. PMID: 27016072.
      Citations: 4     Fields:    Translation:Humans
    25. Karbaschi M, Cooke MS. Novel method for the high-throughput processing of slides for the comet assay. Sci Rep. 2014 Nov 26; 4:7200. PMID: 25425241.
      Citations: 8     Fields:    
    26. Yahirun JJ, Hamplová D. CHILDREN'S UNION STATUS AND CONTACT WITH MOTHERS: A CROSS-NATIONAL STUDY. Demogr Res. 2014 Jan-Jun; 30:1413-1444. PMID: 31618917.
      Citations: 1     Fields:    Translation:Cells
    27. Hu CW, Cooke MS, Tsai YH, Chao MR. 8-Oxo-7,8-dihydroguanine and 8-oxo-7,8-dihydro-2'-deoxyguanosine concentrations in various human body fluids: implications for their measurement and interpretation. Arch Toxicol. 2015 Feb; 89(2):201-10. PMID: 24792325.
      Citations: 8     Fields:    Translation:Humans
    28. Godschalk RW, Ersson C, Stepnik M, Ferlinska M, Palus J, Teixeira JP, Costa S, Jones GD, Higgins JA, Kain J, Möller L, Forchhammer L, Loft S, Lorenzo Y, Collins AR, van Schooten FJ, Laffon B, Valdiglesias V, Cooke M, Mistry V, Karbaschi M, Phillips DH, Sozeri O, Routledge MN, Nelson-Smith K, Riso P, Porrini M, López de Cerain A, Azqueta A, Matullo G, Allione A, Møller P. Variation of DNA damage levels in peripheral blood mononuclear cells isolated in different laboratories. Mutagenesis. 2014 Jul; 29(4):241-9. PMID: 24737269.
      Citations: 1     Fields:    Translation:HumansCells
    29. Rossner P, Mistry V, Singh R, Sram RJ, Cooke MS. Urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine values determined by a modified ELISA improves agreement with HPLC-MS/MS. Biochem Biophys Res Commun. 2013 Nov 01; 440(4):725-30. PMID: 24120947.
      Citations: 7     Fields:    Translation:Humans
    30. Cooke MS, Harry EL, Liljendahl TS, Segerbäck D. DNA nucleotide excision repair, where do all the cyclobutane pyrimidine dimers go? . 2013 May 15; 12(10):1642. PMID: 23603991.
      Citations:    
    31. Ersson C, Møller P, Forchhammer L, Loft S, Azqueta A, Godschalk RW, van Schooten FJ, Jones GD, Higgins JA, Cooke MS, Mistry V, Karbaschi M, Phillips DH, Sozeri O, Routledge MN, Nelson-Smith K, Riso P, Porrini M, Matullo G, Allione A, Stepnik M, Ferlinska M, Teixeira JP, Costa S, Corcuera LA, López de Cerain A, Laffon B, Valdiglesias V, Collins AR, Möller L. An ECVAG inter-laboratory validation study of the comet assay: inter-laboratory and intra-laboratory variations of DNA strand breaks and FPG-sensitive sites in human mononuclear cells. Mutagenesis. 2013 May; 28(3):279-86. PMID: 23446176.
      Citations: 10     Fields:    Translation:HumansCells
    32. Barregard L, Møller P, Henriksen T, Mistry V, Koppen G, Rossner P, Sram RJ, Weimann A, Poulsen HE, Nataf R, Andreoli R, Manini P, Marczylo T, Lam P, Evans MD, Kasai H, Kawai K, Li YS, Sakai K, Singh R, Teichert F, Farmer PB, Rozalski R, Gackowski D, Siomek A, Saez GT, Cerda C, Broberg K, Lindh C, Hossain MB, Haghdoost S, Hu CW, Chao MR, Wu KY, Orhan H, Senduran N, Smith RJ, Santella RM, Su Y, Cortez C, Yeh S, Olinski R, Loft S, Cooke MS. Human and methodological sources of variability in the measurement of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine. Antioxid Redox Signal. 2013 Jun 20; 18(18):2377-91. PMID: 23198723.
      Citations: 27     Fields:    Translation:Humans
    33. Forchhammer L, Ersson C, Loft S, Möller L, Godschalk RW, van Schooten FJ, Jones GD, Higgins JA, Cooke M, Mistry V, Karbaschi M, Collins AR, Azqueta A, Phillips DH, Sozeri O, Routledge MN, Nelson-Smith K, Riso P, Porrini M, Matullo G, Allione A, Stepnik M, Steepnik M, Komorowska M, Teixeira JP, Costa S, Corcuera LA, López de Cerain A, Laffon B, Valdiglesias V, Møller P. Inter-laboratory variation in DNA damage using a standard comet assay protocol. Mutagenesis. 2012 Nov; 27(6):665-72. PMID: 22844078.
      Citations: 14     Fields:    Translation:HumansCells
    34. Lam PM, Mistry V, Marczylo TH, Konje JC, Evans MD, Cooke MS. Rapid measurement of 8-oxo-7,8-dihydro-2'-deoxyguanosine in human biological matrices using ultra-high-performance liquid chromatography-tandem mass spectrometry. Free Radic Biol Med. 2012 May 15; 52(10):2057-63. PMID: 22542794.
      Citations: 14     Fields:    Translation:Humans
    35. Cooke MS. Special issue on DNA oxidation: mechanisms, measurement and consequences. Free Radic Res. 2012 Apr; 46(4):365-6. PMID: 22348649.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    36. Cadet J, Loft S, Olinski R, Evans MD, Bialkowski K, Richard Wagner J, Dedon PC, Møller P, Greenberg MM, Cooke MS. Biologically relevant oxidants and terminology, classification and nomenclature of oxidatively generated damage to nucleobases and 2-deoxyribose in nucleic acids. Free Radic Res. 2012 Apr; 46(4):367-81. PMID: 22263561.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    37. Møller P, Cooke MS, Collins A, Olinski R, Rozalski R, Loft S. Harmonising measurements of 8-oxo-7,8-dihydro-2'-deoxyguanosine in cellular DNA and urine. Free Radic Res. 2012 Apr; 46(4):541-53. PMID: 22117555.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    38. Karbaschi M, Brady NJ, Evans MD, Cooke MS. Immuno-slot blot assay for detection of UVR-mediated DNA damage. Methods Mol Biol. 2012; 920:163-75. PMID: 22941603.
      Citations: 2     Fields:    Translation:Animals
    39. Sutcliffe A, Hollins F, Gomez E, Saunders R, Doe C, Cooke M, Challiss RA, Brightling CE. Increased nicotinamide adenine dinucleotide phosphate oxidase 4 expression mediates intrinsic airway smooth muscle hypercontractility in asthma. Am J Respir Crit Care Med. 2012 Feb 01; 185(3):267-74. PMID: 22108207.
      Citations: 36     Fields:    Translation:Humans
    40. Al-Salmani K, Abbas HH, Schulpen S, Karbaschi M, Abdalla I, Bowman KJ, So KK, Evans MD, Jones GD, Godschalk RW, Cooke MS. Simplified method for the collection, storage, and comet assay analysis of DNA damage in whole blood. Free Radic Biol Med. 2011 Aug 01; 51(3):719-25. PMID: 21658444.
      Citations: 9     Fields:    Translation:HumansCells
    41. Mistry V, Teichert F, Sandhu JK, Singh R, Evans MD, Farmer PB, Cooke MS. Non-invasive assessment of oxidatively damaged DNA: liquid chromatography-tandem mass spectrometry analysis of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine. Methods Mol Biol. 2011; 682:279-89. PMID: 21057935.
      Citations: 3     Fields:    Translation:Humans
    42. Schoenmakers E, Agostini M, Mitchell C, Schoenmakers N, Papp L, Rajanayagam O, Padidela R, Ceron-Gutierrez L, Doffinger R, Prevosto C, Luan J, Montano S, Lu J, Castanet M, Clemons N, Groeneveld M, Castets P, Karbaschi M, Aitken S, Dixon A, Williams J, Campi I, Blount M, Burton H, Muntoni F, O'Donovan D, Dean A, Warren A, Brierley C, Baguley D, Guicheney P, Fitzgerald R, Coles A, Gaston H, Todd P, Holmgren A, Khanna KK, Cooke M, Semple R, Halsall D, Wareham N, Schwabe J, Grasso L, Beck-Peccoz P, Ogunko A, Dattani M, Gurnell M, Chatterjee K. Mutations in the selenocysteine insertion sequence-binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humans. J Clin Invest. 2010 Dec; 120(12):4220-35. PMID: 21084748.
      Citations: 75     Fields:    Translation:HumansAnimalsCells
    43. Henderson PT, Evans MD, Cooke MS. Salvage of oxidized guanine derivatives in the (2'-deoxy)ribonucleotide pool as source of mutations in DNA. Mutat Res. 2010 Nov 28; 703(1):11-7. PMID: 20833264.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    44. Evans MD, Saparbaev M, Cooke MS. DNA repair and the origins of urinary oxidized 2'-deoxyribonucleosides. Mutagenesis. 2010 Sep; 25(5):433-42. PMID: 20522520.
      Citations: 25     Fields:    Translation:HumansCells
    45. Cooke MS, Loft S, Olinski R, Evans MD, Bialkowski K, Wagner JR, Dedon PC, Møller P, Greenberg MM, Cadet J. Recommendations for standardized description of and nomenclature concerning oxidatively damaged nucleobases in DNA. Chem Res Toxicol. 2010 Apr 19; 23(4):705-7. PMID: 20235554.
      Citations: 14     Fields:    Translation:Cells
    46. Greenwood DC, Alwan N, Boylan S, Cade JE, Charvill J, Chipps KC, Cooke MS, Dolby VA, Hay AW, Kassam S, Kirk SF, Konje JC, Potdar N, Shires S, Simpson N, Taub N, Thomas JD, Walker J, White KL, Wild CP. Caffeine intake during pregnancy, late miscarriage and stillbirth. Eur J Epidemiol. 2010 Apr; 25(4):275-80. PMID: 20306287.
      Citations: 19     Fields:    Translation:Humans
    47. Garratt LW, Mistry V, Singh R, Sandhu JK, Sheil B, Cooke MS, Sly PD. Interpretation of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine is adversely affected by methodological inaccuracies when using a commercial ELISA. Free Radic Biol Med. 2010 Jun 01; 48(11):1460-4. PMID: 20171272.
      Citations: 9     Fields:    Translation:Humans
    48. Evans MD, Singh R, Mistry V, Farmer PB, Cooke MS. Analysis of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine by liquid chromatography-tandem mass spectrometry. Methods Mol Biol. 2010; 610:341-51. PMID: 20013188.
      Citations: 2     Fields:    Translation:Cells
    49. Evans MD, Olinski R, Loft S, Cooke MS. Toward consensus in the analysis of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine as a noninvasive biomarker of oxidative stress. FASEB J. 2010 Apr; 24(4):1249-60. PMID: 19966135.
      Citations: 28     Fields:    Translation:Humans
    50. Cooke MS, Henderson PT, Evans MD. Sources of extracellular, oxidatively-modified DNA lesions: implications for their measurement in urine. J Clin Biochem Nutr. 2009 Nov; 45(3):255-70. PMID: 19902015.
      Citations:    
    51. Cooke MS. A commentary on "Urea, the most abundant component in urine, cross-reacts with a commercial 8-OH-dG ELISA kit and contributes to overestimation of urinary 8-OH-dG". What is ELISA detecting? Free Radic Biol Med. 2009 Jul 01; 47(1):30-1. PMID: 19362140.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    52. Cooke MS, Barregard L, Mistry V, Potdar N, Rozalski R, Gackowski D, Siomek A, Foksinski M, Svoboda P, Kasai H, Konje JC, Sallsten G, Evans MD, Olinski R. Interlaboratory comparison of methodologies for the measurement of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine. Biomarkers. 2009 Mar; 14(2):103-10. PMID: 19330588.
      Citations: 6     Fields:    Translation:Humans
    53. Song R, Duarte TL, Almeida GM, Farmer PB, Cooke MS, Zhang W, Sheng G, Fu J, Jones GD. Cytotoxicity and gene expression profiling of two hydroxylated polybrominated diphenyl ethers in human H295R adrenocortical carcinoma cells. Toxicol Lett. 2009 Feb 25; 185(1):23-31. PMID: 19095052.
      Citations: 7     Fields:    Translation:HumansCells
    54. Duarte TL, Cooke MS, Jones GD. Gene expression profiling reveals new protective roles for vitamin C in human skin cells. Free Radic Biol Med. 2009 Jan 01; 46(1):78-87. PMID: 18973801.
      Citations: 27     Fields:    Translation:HumansCells
    55. Evans MD, Singh R, Mistry V, Sandhu K, Farmer PB, Cooke MS. Analysis of urinary 8-oxo-7,8-dihydro-purine-2'-deoxyribonucleosides by LC-MS/MS and improved ELISA. Free Radic Res. 2008 Oct; 42(10):831-40. PMID: 18985483.
      Citations: 11     Fields:    Translation:Humans
    56. Cooke MS, Duarte TL, Cooper D, Chen J, Nandagopal S, Evans MD. Combination of azathioprine and UVA irradiation is a major source of cellular 8-oxo-7,8-dihydro-2'-deoxyguanosine. DNA Repair (Amst). 2008 Dec 01; 7(12):1982-9. PMID: 18793759.
      Citations: 19     Fields:    Translation:HumansCells
    57. Loft S, Møller P, Cooke MS, Rozalski R, Olinski R. Antioxidant vitamins and cancer risk: is oxidative damage to DNA a relevant biomarker? Eur J Nutr. 2008 May; 47 Suppl 2:19-28. PMID: 18458832.
      Citations: 18     Fields:    Translation:HumansCells
    58. Mistry N, Bevan RJ, Cooke MS, Evans MD, Halligan EP, Lowes DA, Nichol K, Lunec J. Antiserum detection of reactive carbonyl species-modified DNA in human colonocytes. Free Radic Res. 2008 Apr; 42(4):344-53. PMID: 18404533.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    59. Cooke MS, Olinski R, Loft S. Measurement and meaning of oxidatively modified DNA lesions in urine. Cancer Epidemiol Biomarkers Prev. 2008 Jan; 17(1):3-14. PMID: 18199707.
      Citations: 48     Fields:    Translation:HumansCells
    60. Cooke MS, Evans MD. 8-Oxo-deoxyguanosine: reduce, reuse, recycle? Proc Natl Acad Sci U S A. 2007 Aug 21; 104(34):13535-6. PMID: 17699620.
      Citations: 15     Fields:    
    61. Cooke MS, Osborne JE, Singh R, Mistry V, Farmer PB, Evans MD, Hutchinson PE. Evidence that oxidative stress is a risk factor for the development of squamous cell carcinoma in renal transplant patients. Free Radic Biol Med. 2007 Nov 01; 43(9):1328-34. PMID: 17893046.
      Citations: 2     Fields:    Translation:Humans
    62. Kulkarni N, Cooke MS, Grigg J. Neutrophils in induced sputum from healthy children: role of interleukin-8 and oxidative stress. Respir Med. 2007 Oct; 101(10):2108-12. PMID: 17618102.
      Citations: 2     Fields:    Translation:HumansCells
    63. Grigg J, Cooke MS, Panickar JR. Case 3-2007: a boy with respiratory insufficiency. N Engl J Med. 2007 May 31; 356(22):2329-30; author reply 2330. PMID: 17542074.
      Citations:    Fields:    Translation:Humans
    64. Halligan EP, Lowes D, Mistry N, Dove R, Cooke M, Evans M, Lunec J. A comparison of the gene expression profiles of CRL-1807 colonocytes exposed to endogenous AAPH-generated peroxides and exogenous peroxides from heated oil. Redox Rep. 2007; 12(1):86-90. PMID: 17263917.
      Citations: 1     Fields:    Translation:HumansCells
    65. Cooke MS, Singh R, Hall GK, Mistry V, Duarte TL, Farmer PB, Evans MD. Evaluation of enzyme-linked immunosorbent assay and liquid chromatography-tandem mass spectrometry methodology for the analysis of 8-oxo-7,8-dihydro-2'-deoxyguanosine in saliva and urine. Free Radic Biol Med. 2006 Dec 15; 41(12):1829-36. PMID: 17157185.
      Citations: 13     Fields:    Translation:Humans
    66. Olinski R, Rozalski R, Gackowski D, Foksinski M, Siomek A, Cooke MS. Urinary measurement of 8-OxodG, 8-OxoGua, and 5HMUra: a noninvasive assessment of oxidative damage to DNA. Antioxid Redox Signal. 2006 May-Jun; 8(5-6):1011-9. PMID: 16771691.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    67. Cooke MS, Rozalski R, Dove R, Gackowski D, Siomek A, Evans MD, Olinski R. Evidence for attenuated cellular 8-oxo-7,8-dihydro-2'-deoxyguanosine removal in cancer patients. Biol Chem. 2006 Apr; 387(4):393-400. PMID: 16606337.
      Citations: 3     Fields:    Translation:HumansCells
    68. Cooke MS, Robson A. Immunochemical detection of UV-induced DNA damage and repair. Methods Mol Biol. 2006; 314:215-28. PMID: 16673884.
      Citations:    Fields:    Translation:HumansCells
    69. Cooke MS, Olinski R, Evans MD. Does measurement of oxidative damage to DNA have clinical significance? Clin Chim Acta. 2006 Mar; 365(1-2):30-49. PMID: 16214123.
      Citations: 49     Fields:    Translation:Humans
    70. Cooke MS, Evans MD, Dove R, Rozalski R, Gackowski D, Siomek A, Lunec J, Olinski R. DNA repair is responsible for the presence of oxidatively damaged DNA lesions in urine. Mutat Res. 2005 Jul 01; 574(1-2):58-66. PMID: 15914207.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    71. Habayeb OM, Taylor AH, Evans MD, Cooke MS, Taylor DJ, Bell SC, Konje JC. Plasma levels of the endocannabinoid anandamide in women--a potential role in pregnancy maintenance and labor? J Clin Endocrinol Metab. 2004 Nov; 89(11):5482-7. PMID: 15531501.
      Citations: 23     Fields:    Translation:Humans
    72. Evans MD, Dizdaroglu M, Cooke MS. Oxidative DNA damage and disease: induction, repair and significance. Mutat Res. 2004 Sep; 567(1):1-61. PMID: 15341901.
      Citations: 253     Fields:    Translation:HumansCells
    73. Evans MD, Cooke MS. Factors contributing to the outcome of oxidative damage to nucleic acids. Bioessays. 2004 May; 26(5):533-42. PMID: 15112233.
      Citations: 54     Fields:    Translation:Cells
    74. Cooke MS, Podmore ID, Mistry N, Evans MD, Herbert KE, Griffiths HR, Lunec J. Immunochemical detection of UV-induced DNA damage and repair. J Immunol Methods. 2003 Sep; 280(1-2):125-33. PMID: 12972193.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    75. Cooke MS, Evans MD, Dizdaroglu M, Lunec J. Oxidative DNA damage: mechanisms, mutation, and disease. FASEB J. 2003 Jul; 17(10):1195-214. PMID: 12832285.
      Citations: 667     Fields:    Translation:HumansCells
    76. Karakoula A, Evans MD, Podmore ID, Hutchinson PE, Lunec J, Cooke MS. Quantification of UVR-induced DNA damage: global- versus gene-specific levels of thymine dimers. J Immunol Methods. 2003 Jun 01; 277(1-2):27-37. PMID: 12799037.
      Citations: 2     Fields:    Translation:Humans
    77. Mistry N, Podmore I, Cooke M, Butler P, Griffiths H, Herbert K, Lunec J. Novel monoclonal antibody recognition of oxidative DNA damage adduct, deoxycytidine-glyoxal. Lab Invest. 2003 Feb; 83(2):241-50. PMID: 12594238.
      Citations: 4     Fields:    Translation:AnimalsCells
    78. Evans MD, Butler JM, Nicoll K, Cooke MS, Lunec J. 17 beta-Oestradiol attenuates nucleotide excision repair. FEBS Lett. 2003 Jan 30; 535(1-3):153-8. PMID: 12560095.
      Citations: 3     Fields:    Translation:HumansCells
    79. Cooke MS, Mistry N, Ahmad J, Waller H, Langford L, Bevan RJ, Evans MD, Jones GD, Herbert KE, Griffiths HR, Lunec J. Deoxycytidine glyoxal: lesion induction and evidence of repair following vitamin C supplementation in vivo. Free Radic Biol Med. 2003 Jan 15; 34(2):218-25. PMID: 12521603.
      Citations: 3     Fields:    Translation:HumansCellsCTClinical Trials
    80. Lunec J, Holloway K, Cooke M, Evans M. Redox-regulation of DNA repair. Biofactors. 2003; 17(1-4):315-24. PMID: 12897453.
      Citations:    Fields:    Translation:Cells
    81. Cooke MS, Lunec J, Evans MD. Progress in the analysis of urinary oxidative DNA damage. Free Radic Biol Med. 2002 Dec 15; 33(12):1601-14. PMID: 12488129.
      Citations: 13     Fields:    Translation:Humans
    82. Lunec J, Holloway KA, Cooke MS, Faux S, Griffiths HR, Evans MD. Urinary 8-oxo-2'-deoxyguanosine: redox regulation of DNA repair in vivo? Free Radic Biol Med. 2002 Oct 01; 33(7):875-85. PMID: 12361799.
      Citations: 21     Fields:    Translation:HumansCells
    83. Cooke MS, Evans MD, Lunec J. DNA repair: insights from urinary lesion analysis. Free Radic Res. 2002 Sep; 36(9):929-32. PMID: 12448817.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    84. Griffiths HR, Møller L, Bartosz G, Bast A, Bertoni-Freddari C, Collins A, Cooke M, Coolen S, Haenen G, Hoberg AM, Loft S, Lunec J, Olinski R, Parry J, Pompella A, Poulsen H, Verhagen H, Astley SB. Biomarkers. Mol Aspects Med. 2002 Feb-Jun; 23(1-3):101-208. PMID: 12079771.
      Citations: 45     Fields:    Translation:HumansAnimalsCells
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